Although these reports were small case series and there are no data comparing the efficacy and safety of the various endoscopic hemostatic methods available, evidence of the safety and efficacy of clipping for colonic diverticular bleeding has been provided. In recent times, the impact of clipping for this disorder has been increasing worldwide. Colonoscopic hemostatic methods including adrenaline injection, thermal and electrical coagulation or combinations of these have been applied, until first reports of the efficacy of endoscopic clipping for colonic diverticular bleeding. Urgent colonoscopy offers not only a diagnostic method but also a therapeutic maneuver for its management. ![]() In this review, we discuss the safety and efficacy of endoscopic clipping for the management of colonic diseases.ĭiverticular bleeding is one of the most common causes of lower gastrointestinal bleeding. More recently, clipping has been widely applied to the hemostasis of lower gastrointestinal bleeding and non-hemostatic treatments including closing mucosal defects, leaks and perforations, and marking lesions prior to radiotherapy or surgery. Currently, clipping is an established mandatory technique of endoscopic hemostasis for nonvariceal upper gastrointestinal bleeding, including Mallory-Weiss syndrome, duodenal diverticular bleeding, Dieulafoy lesions of the stomach and duodenum, as well as bleeding peptic ulcers. ![]() Numerous trials and a meta-analysis have shown that clipping is an effective hemostatic method for bleeding peptic ulcers, with high rates of primary hemostasis (85%-100%), low rebleeding rates (2%-20%) and an excellent safety record. For more than two decades, endoclips have become available worldwide with continuous technical improvements. ![]() Endoscopic clipping devices were developed by Hachisu in cooperation with Olympus Co.
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